Adverse childhood experiences and risk of cancer during adulthood: A systematic review and meta-analysis.

  title={Adverse childhood experiences and risk of cancer during adulthood: A systematic review and meta-analysis.},
  author={Zhao Hu and Atipatsa Chiwanda Kaminga and Jun Yang and Jiefeng Liu and Huilan Xu},
  journal={Child abuse \& neglect},

Childhood Adversity Among Adults With Chronic Pain

Findings suggest that the number and the type of self-reported ACE(s) are associated with pain-related variables and psychosocial functioning in adults with chronic pain.

Maternal adverse childhood experiences before pregnancy are associated with epigenetic aging changes in their children.

The data suggests that maternal preconceptions ACEs are associated with biological aging in their offspring in childhood and that preconception ACEs have differential relationships with EAA measures, suggesting different physiologic utilities of EEA measures.

Using Microbiome-Based Approaches to Deprogram Chronic Disorders and Extend the Healthspan following Adverse Childhood Experiences

To reverse the tragedy of ACE-programmed NCDs and premature aging, managing the human holobiont microbiome should become a routine part of healthcare and preventative medicine across the life course.



The Association Between Adverse Childhood Experiences and Risk of Cancer in Adulthood: A Systematic Review of the Literature

It is suggested that childhood adversity in various forms may increase a person’s cancer risk.

Active and passive smoking and risk of breast cancer: a meta-analysis

A meta-analysis of observational studies on tobacco smoking and breast cancer occurrence was conducted based on systematic searches for studies with retrospective (case–control) and prospective (cohort) designs, and the results were stable across different subgroup analyses.

Association between adverse childhood experiences and adult diseases in older adults: a comparative cross-sectional study in Japan and Finland

The association between ACEs and poor SRH, adult diseases and health behaviours was similar among older adults in both Japan and Finland, suggesting that the impact of ACEs on health is noteworthy and consistent across cultural and social environments.

Gender Differences in the Association between Adverse Childhood Experiences and Cancer.

Childhood adversity as a risk for cancer: findings from the 1958 British birth cohort study

Findings suggest that cancer risk may be influenced by exposure to stressful conditions and events early on in life, potentially important in furthering the understanding of cancer aetiology, and consequently in redirecting scientific research and developing appropriate prevention policies.

Adverse childhood experiences are associated with the risk of lung cancer: a prospective cohort study

The ACE score showed a graded relationship to smoking behaviors and the increase in risk may only be partly explained by smoking suggesting other possible mechanisms by which ACEs may contribute to the occurrence of lung cancer.

Cancer in working-age is not associated with childhood adversities

There is no cause to attribute development of cancer in working age to childhood adversities, and this information may also give relief to other family members.

Alcohol consumption and site-specific cancer risk: a comprehensive dose–response meta-analysis

Alcohol increases risk of cancer of oral cavity and pharynx, oesophagus, colorectum, liver, larynx and female breast, and there is accumulating evidence that alcohol drinking is associated with some other cancers such as pancreas and prostate cancer and melanoma.