Adverse childhood experiences and associated health outcomes: A systematic review and meta-analysis.

  title={Adverse childhood experiences and associated health outcomes: A systematic review and meta-analysis.},
  author={Kaitlyn Petruccelli and Joshua Davis and Tara Berman},
  journal={Child abuse \& neglect},

Screening for adverse childhood experiences in preventive medicine settings: a scoping review

This review found that the following factors increase the likelihood that ACE screenings can be successfully integrated into healthcare settings: staff trainings that increase provider confidence and competence in administering screenings, accessible and robust mental health resources, and organizational support.

Adverse Childhood Experiences Are Associated with Reduced Psychological Resilience in Youth: A Systematic Review and Meta-Analysis

Background: Adverse childhood experiences (ACEs) are presumed to influence internalizing and externalizing behaviors that can significantly debilitate long-term biopsychological development in

The Associations Between Maternal Adverse Childhood Experiences, Substance Use During Pregnancy and Poor Infant Outcomes: A Protocol for Systematic Review and Meta-Analysis

This review will provide supporting evidence on the body of literature exploring the long-term and intergenerational consequences of adverse childhood experiences to help inform policies and interventions related to maternal health as well as early childhood development.

Associations of adverse and positive childhood experiences with adult physical and mental health and risk behaviours in Slovenia

Above median PCEs attenuate the association between ACEs and poor self-rated health, mental health problems, and physical inactivity in later life, and are negatively associated with these health problems even in the concurrent presence of ACEs.

Systematic Review and Meta-Analysis of the Effect of Adverse Childhood Experiences (ACEs) on Brain-Derived Neurotrophic Factor (BDNF) Levels

A systematic review and meta-analysis of the impact of ACE exposure on Brain Derived Neurotrophic Factor levels - a neural biomarker associated with the onset of mood disorders found no significant difference between ACE-exposed and unexposed groups.

Prevalence of Adverse Childhood Experiences in the First Decade of Life: A Study in the Portuguese Cohort, Generation XXI

This study estimates the prevalence of ACEs in children, addressing associated sociodemographic characteristics and examining the relationship ofACEs with the child’s health and behaviors, and observed that the dimensions of Aces could be identified at 10 years of age.

Association of Childhood Adversity With Morbidity and Mortality in US Adults: A Systematic Review.

The results of this systematic review suggest that CA is a leading contributor to morbidity and mortality in the US and may be considered a preventable determinant of mortality.

Does screening or routine enquiry for adverse childhood experiences (ACEs) meet criteria for a screening programme? A rapid evidence summary.

There is currently insufficient evidence to recommend the implementation of a screening programme for ACEs, and further research is needed to determine whether routine enquiry can improve morbidity, mortality, health and wellbeing.



Health consequences of adverse childhood experiences: A systematic review

NPs are encouraged to incorporate assessment of patients’ childhood history in routine primary care and to consider the evidence that supports a relationship between ACEs and health and although difficult, talking about patient's childhood experiences may positively influence health outcomes.

Adverse childhood experiences and self-reported liver disease: new insights into the causal pathway.

The ACE score showed a graded relationship to therisk of liver disease that appears to be mediated substantially by behaviors that increase the risk of viral and alcohol-induced liver disease.

Association of alcohol consumption with selected cardiovascular disease outcomes: a systematic review and meta-analysis

Light to moderate alcohol consumption is associated with a reduced risk of multiple cardiovascular outcomes, and the lowest risk of coronary heart disease mortality occurred with 1–2 drinks a day, but for stroke mortality it occurred with ≤1 drink per day.

Insights Into Causal Pathways for Ischemic Heart Disease: Adverse Childhood Experiences Study

A dose-response relation of ACEs to IHD and a relation between almost all individual ACEs and IHD is found and psychological factors appear to be more important than traditional risk factors in mediating the relation ofACEs to the risk of IHD.

Adverse childhood experiences: retrospective study to determine their impact on adult health behaviours and health outcomes in a UK population.

That ACEs are linked to involvement in violence, early unplanned pregnancy, incarceration, and unemployment suggests a cyclic effect where those with higher ACE counts have higher risks of exposing their own children to ACEs.

Adverse childhood experiences and health-related quality of life in adulthood: revelations from a community needs assessment

Stress and sleep disturbances may represent later consequences of childhood adversity that modulate adult quality of life as they related to  the relationship between ACE and excessive unhealthy days.