Adverse childhood experiences and associated health outcomes: A systematic review and meta-analysis.

@article{Petruccelli2019AdverseCE,
  title={Adverse childhood experiences and associated health outcomes: A systematic review and meta-analysis.},
  author={Kaitlyn Petruccelli and Joshua Davis and Tara Berman},
  journal={Child abuse \& neglect},
  year={2019},
  volume={97},
  pages={
          104127
        }
}

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...

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NPs are encouraged to incorporate assessment of patients’ childhood history in routine primary care and to consider the evidence that supports a relationship between ACEs and health and although difficult, talking about patient's childhood experiences may positively influence health outcomes.

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The ACE score showed a graded relationship to therisk of liver disease that appears to be mediated substantially by behaviors that increase the risk of viral and alcohol-induced liver disease.

Association of alcohol consumption with selected cardiovascular disease outcomes: a systematic review and meta-analysis

Light to moderate alcohol consumption is associated with a reduced risk of multiple cardiovascular outcomes, and the lowest risk of coronary heart disease mortality occurred with 1–2 drinks a day, but for stroke mortality it occurred with ≤1 drink per day.

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