Adverse childhood experiences (ACEs) relate to blunted cardiovascular and cortisol reactivity to acute laboratory stress: A systematic review and meta-analysis

  title={Adverse childhood experiences (ACEs) relate to blunted cardiovascular and cortisol reactivity to acute laboratory stress: A systematic review and meta-analysis},
  author={Ryan C. Brindle and Alexander T Pearson and Annie T. Ginty},
  journal={Neuroscience \& Biobehavioral Reviews},

Lifetime Stressor Exposure and Psychophysiological Reactivity and Habituation to Repeated Acute Social Stressors.

This study addressed whether lifetime stressor exposure was associated with psychophysiological reactivity and habituation to a novel laboratory-based stressor. Eighty-six participants (Mage = 23.31

Early Life SES, Childhood Trauma Exposures, and Cardiovascular Responses to Daily Life Stressors in Middle-aged Adults.

The impacts of early childhood experiences on cardiovascular responses may vary by type of daily stress experience, and multilevel models showed no main effects of early life SES or childhood trauma on ambulatory measures of cardiovascular responses to daily life stress.

Adolescent girls' cardiovascular responses to peer rejection: exploring the impact of early life stress.

Detrimental effects of early life stress on cardiovascular health are evident in adolescence. Cardiovascular reactivity and recovery in response to interpersonal stress may be a mechanism. This study

Stress and reward: A multimodal assessment of childhood sexual abuse

Does childhood trauma impact daily psychobiological stress in somatic symptom disorder? An ambulatory assessment study

This study provides preliminary evidence for elevated daily stress and blunted sympathetic and hypothalamic-pituitary-adrenal axis activity in individuals with somatic symptom disorder and depressive disorders.

Childhood Trauma and Cortisol Reactivity: An Investigation of the Role of Task Appraisals

Background Childhood adversity is linked to adverse health in adulthood. One posited mechanistic pathway is through physiological responses to acute stress. Childhood adversity has been previously



Cardiovascular Stress Reactivity and Health: Recent Questions and Future Directions

This narrative review and opinion paper summarises and considers where the reactivity hypothesis and reactivity research is now in terms of the usefulness, and elucidates the gaps in knowledge and key research issues that still remain to be addressed.

Association of Adverse Childhood Experiences With Cardiovascular Disease Later in Life: A Review.

This review summarizes the evidence regarding the association of ACEs with CVD and the accompanying diagnostic and therapeutic approaches in the adult population and identifies methods of mitigating the health consequences ofACEs that may lead to better cardiovascular outcomes.

The Value of Dimensional Models of Early Experience: Thinking Clearly About Concepts and Categories

We review the three prevailing approaches—specificity, cumulative risk, and dimensional models—to conceptualizing the developmental consequences of early-life adversity and address fundamental