Adverse childhood experiences (ACEs), genetic polymorphisms and neurochemical correlates in experimentation with psychotropic drugs among adolescents.

@article{Somaini2011AdverseCE,
  title={Adverse childhood experiences (ACEs), genetic polymorphisms and neurochemical correlates in experimentation with psychotropic drugs among adolescents.},
  author={Lorenzo Somaini and Claudio Donnini and Matteo Manfredini and Maria Augusta Raggi and Maria Addolorata Saracino and Maria Lidia Gerra and Mario Amore and Claudio Leonardi and Giovanni Serpelloni and Gilberto Gerra},
  journal={Neuroscience and biobehavioral reviews},
  year={2011},
  volume={35 8},
  pages={1771-8}
}
Epidemiological and clinical data show frequent associations between adverse childhood experiences (ACEs) and substance abuse susceptibility particularly in adolescents. A large body of evidences suggests that the possible dysregulation of neuroendocrine responses as well as neurotransmitters function induced by childhood traumatic experiences and emotional… CONTINUE READING