Adverse cardiovascular events during treatment with pioglitazone and rosiglitazone: population based cohort study

@inproceedings{Juurlink2009AdverseCE,
  title={Adverse cardiovascular events during treatment with pioglitazone and rosiglitazone: population based cohort study},
  author={David N Juurlink and Tara Gomes and Lorraine L. Lipscombe and Peter C. Austin and Janet E. Hux and Muhammad M Mamdani},
  booktitle={BMJ},
  year={2009}
}
OBJECTIVE To compare the risk of acute myocardial infarction, heart failure, and death in patients with type 2 diabetes treated with rosiglitazone and pioglitazone. DESIGN Retrospective cohort study. SETTING Ontario, Canada. PARTICIPANTS Outpatients aged 66 years and older who were started on rosiglitazone or pioglitazone between 1 April 2002 and 31 March 2008. MAIN OUTCOME MEASURE Composite of death or hospital admission for either acute myocardial infarction or heart failure. In a… CONTINUE READING