Adverse Effects of High Doses of Intravenous Alpha Lipoic Acid on Liver Mitochondria

  title={Adverse Effects of High Doses of Intravenous Alpha Lipoic Acid on Liver Mitochondria},
  author={Michael Vigil and Burton M. Berkson and Ana Patricia Garcia},
  booktitle={Global advances in health and medicine},
Alpha lipoic acid (ALA, thioctic acid), among other actions, is an essential coenzyme in the conversion of pyruvate to acetyl co-enzyme A. Therefore, it is necessary for the production of energy for aerobic organisms. Scientists have found that it can be used medically to help regenerate liver tissue, reverse the complications of diabetes mellitus, slow or stop the growth of cancer cells, and chelate heavy metals, among other actions. In this article, the authors describe the cellular… CONTINUE READING
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A dose escalation toxicity study of DL-6-8 thioctic acid (lipoic acid) in Rhesus monkeys

RC Couch, MA Vigil M. Thomas, G. Sibert
Annual Meeting of Toxicology; Cincinnati, • 1997

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