Adverse Effects of Acne Medications: Recognition and Management

  title={Adverse Effects of Acne Medications: Recognition and Management},
  author={Mollie D. Oudenhoven and Megan A. Kinney and Diana B. McShane and Craig Burkhart and Dean S Morrell},
  journal={American Journal of Clinical Dermatology},
Acne vulgaris is a very common chronic inflammatory disease of the skin. The clinical features of acne range from non-inflammatory comedones to inflammatory nodules. While often perceived as an adolescent disease, the prevalence remains high into adulthood, and the manifestations can have detrimental psychosocial effects. It is therefore not surprising that many patients are motivated to seek treatment. The existing treatment strategies for acne are complex due to the multifactorial… 

Carefully manage adverse effects of acne treatments to prevent significant harm

Many treatments strategies are available for acne vulgaris, a common chronic skin disorder, but appropriate management requires appropriate management to prevent significant harm to the patient whilst providing effective treatment.

The immunomodulatory potential of phage therapy to treat acne: a review on bacterial lysis and immunomodulation

Phage therapy to treat acne can be a suitable therapeutic alternative to C. acnes control, which in turn can aid to restore the skin’s balance of microbiota.

Clinical Pharmacology and Safety of Trifarotene, a First‐in‐Class RARγ‐Selective Topical Retinoid

Results showed that trifarotene 50 µg/g cream is well tolerated and safe, even when applied under maximized conditions in adults and pediatric acne patients presenting with severe acne.

Targeting Acne Bacteria and Wound Healing In Vitro Using Plectranthus aliciae, Rosmarinic Acid, and Tetracycline Gold Nanoparticles

Green synthesised gold nanoparticles of rosmarinic acid could potentially be used for treating wounds and antibacterial activity or biofilm inhibition was observed for the nanoparticles tested on the multispecies C. acnes and S. epidermis systems, and these samples had potential wound closure activity.

Effects of herbal multicomponent dietary supplement in experimental pneumonia

Application of multi-component herbal dietary supplement for rats with pneumonia created positive changes in diminishing lung tissue injury, decreasing ROS generation in blood, lung and liver tissue and decreasing pro-inflammatory cytokine expression of TNF-α and Il-6.

Antibacterial hydrogel containing Piper betle L. extract for acne treatment, an ex vivo investigation

The hydrogel showed higher antibacterial activity than the positive controls in both gram-positive and gram-negative bacteria, and could become a potential pharmaceutical product for acne treatment.

A randomized, double‐blind, placebo‐controlled trial to determine the efficacy and safety of lactoferrin with vitamin E and zinc as an oral therapy for mild to moderate acne vulgaris

A twice daily regimen of lactoferrin with vitamin E and zinc significantly reduced acne lesions in people with mild to moderate acne vulgaris.

Efficacy and Tolerability of a Combined 445nm and 630nm Over-the-counter Light Therapy Mask with and without Topical Salicylic Acid versus Topical Benzoyl Peroxide for the Treatment of Mild-to-moderate Acne Vulgaris.

445nm/630nm light therapy mask appears to be a safe and effective therapy for mild-to-moderate acne.

Chinese Guidelines for the Management of Acne Vulgaris: 2019 Update #

  • Medicine
    International Journal of Dermatology and Venereology
  • 2019



Diagnosis and treatment of acne.

Isotretinoin is reserved for use in the treatment of the most severe or refractory cases of inflammatory acne, and must by prescribed by a physician who is a registered member of the manufacturer's System to Manage Accutane-Related Teratogenicity program.

Acne vulgaris

A streamlined outline of treatment intended for the non-specialist is provided for acne, which has clear detrimental psychosocial effects and may lead to permanent scarring.

Topical Drug Treatment in Acne

More and more evidence comes up that topical antiandrogenic agents will soon be available to treat the important factor seborrhea, because patients with marked hyperseborRhea frequently relapse.

Antibacterial Therapy for Acne

  • H. Tan
  • Medicine
    American journal of clinical dermatology
  • 2003
A number of measures should be undertaken to help prevent the development of resistance, especially with concerns that Propionibacterium acnes can transfer antibacterials resistance to other bacteria within the resident skin flora.

Treatment of acne vulgaris.

The best evidence available for individualized treatment of acne is reviewed to review, with a focus on randomized controlled trials, meta-analyses, and other systematic reviews.

Acne: systemic treatment.

Solodyn and Updates on Topical and Oral Therapies for Acne

The most recent developments in acne pathophysiology are summarized, as the concern for antibiotic resistance grows, and treatments involving nonantibiotic therapies are growing in popularity.

Topical Acne Drugs

Animal data support avoidance of many topical agents, particularly known teratogens such as retinoids and salicylic acid, in pregnant women, and recommend caution in special circumstances, such as during childhood, pregnancy, lactation and concomitant therapy with other drugs, because relevant studies are lacking.

Acne fulminans and erythema nodosum during isotretinoin therapy responding to dapsone

A patient who developed acne fulminans and erythema nodosum within 3 weeks of starting isotretinoin and then responded to dapsone without oral steroids is reported.