Adverse Effects of Acne Medications: Recognition and Management

@article{Oudenhoven2015AdverseEO,
  title={Adverse Effects of Acne Medications: Recognition and Management},
  author={Mollie D. Oudenhoven and Megan A. Kinney and Diana B. McShane and Craig Burkhart and Dean S Morrell},
  journal={American Journal of Clinical Dermatology},
  year={2015},
  volume={16},
  pages={231-242}
}
Acne vulgaris is a very common chronic inflammatory disease of the skin. The clinical features of acne range from non-inflammatory comedones to inflammatory nodules. While often perceived as an adolescent disease, the prevalence remains high into adulthood, and the manifestations can have detrimental psychosocial effects. It is therefore not surprising that many patients are motivated to seek treatment. The existing treatment strategies for acne are complex due to the multifactorial… 

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References

SHOWING 1-10 OF 130 REFERENCES

Diagnosis and treatment of acne.

Isotretinoin is reserved for use in the treatment of the most severe or refractory cases of inflammatory acne, and must by prescribed by a physician who is a registered member of the manufacturer's System to Manage Accutane-Related Teratogenicity program.

Acne vulgaris

A streamlined outline of treatment intended for the non-specialist is provided for acne, which has clear detrimental psychosocial effects and may lead to permanent scarring.

Topical Drug Treatment in Acne

More and more evidence comes up that topical antiandrogenic agents will soon be available to treat the important factor seborrhea, because patients with marked hyperseborRhea frequently relapse.

Antibacterial Therapy for Acne

  • H. Tan
  • Medicine
    American journal of clinical dermatology
  • 2003
A number of measures should be undertaken to help prevent the development of resistance, especially with concerns that Propionibacterium acnes can transfer antibacterials resistance to other bacteria within the resident skin flora.

Treatment of acne vulgaris.

The best evidence available for individualized treatment of acne is reviewed to review, with a focus on randomized controlled trials, meta-analyses, and other systematic reviews.

Acne: systemic treatment.

Solodyn and Updates on Topical and Oral Therapies for Acne

The most recent developments in acne pathophysiology are summarized, as the concern for antibiotic resistance grows, and treatments involving nonantibiotic therapies are growing in popularity.

Topical Acne Drugs

Animal data support avoidance of many topical agents, particularly known teratogens such as retinoids and salicylic acid, in pregnant women, and recommend caution in special circumstances, such as during childhood, pregnancy, lactation and concomitant therapy with other drugs, because relevant studies are lacking.

Acne fulminans and erythema nodosum during isotretinoin therapy responding to dapsone

A patient who developed acne fulminans and erythema nodosum within 3 weeks of starting isotretinoin and then responded to dapsone without oral steroids is reported.
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