Adverse Drug Reactions in Children: The Double-Edged Sword of Therapeutics.

  title={Adverse Drug Reactions in Children: The Double-Edged Sword of Therapeutics.},
  author={Abdelbaset A. Elzagallaai and Mje Greff and Michael John Rieder},
  journal={Clinical pharmacology and therapeutics},
  volume={101 6},
Adverse drug reactions (ADRs) represent a major health problem worldwide, with high morbidity and mortality rates. ADRs are classified into Type A (augmented) and Type B (bizarre) ADRs, with the former group being more common and the latter less common but often severe and clinically more problematic due to their unpredictable nature and occurrence at any dose. Pediatric populations are especially vulnerable to ADRs due to the lack of data for this age group from the drug development process… CONTINUE READING
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