Adverse Childhood Experiences Are Associated With Migraine and Vascular Biomarkers

@article{Tietjen2012AdverseCE,
  title={Adverse Childhood Experiences Are Associated With Migraine and Vascular Biomarkers},
  author={Gretchen E. Tietjen and Jagdish Khubchandani and Nabeel A Herial and Kavit Shah},
  journal={Headache: The Journal of Head and Face Pain},
  year={2012},
  volume={52}
}
Objectives.— Migraine is a risk factor for stroke in young women. Biomarker studies implicate endothelial activation as a possible mechanism. Emerging relationships of childhood adversity with migraine, and with inflammation, a component of endothelial activation, suggest that it may play a role in the migraine–stroke association. Our objective is to evaluate the relationship between adverse childhood experiences (ACEs), migraine, and vascular biomarker levels in premenopausal women. 

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