Adverse Childhood Experiences Are Associated With Migraine and Vascular Biomarkers

  title={Adverse Childhood Experiences Are Associated With Migraine and Vascular Biomarkers},
  author={Gretchen E. Tietjen and Jagdish Khubchandani and Nabeel A Herial and Kavit Shah},
  journal={Headache: The Journal of Head and Face Pain},
Objectives.— Migraine is a risk factor for stroke in young women. Biomarker studies implicate endothelial activation as a possible mechanism. Emerging relationships of childhood adversity with migraine, and with inflammation, a component of endothelial activation, suggest that it may play a role in the migraine–stroke association. Our objective is to evaluate the relationship between adverse childhood experiences (ACEs), migraine, and vascular biomarker levels in premenopausal women. 

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Epidemiology and Treatment of Menstrual Migraine and Migraine During Pregnancy and Lactation: A Narrative Review

  • R. Burch
  • Psychology, Medicine
  • 2019
The evidence for sex differences in the expression of migraine across the reproductive epoch is described; the epidemiology of migraine during pregnancy, lactation, and menses is reviewed; and the available evidence for safety and efficacy of acute treatments during pregnancy and lactation and for menstrual migraine is summarized.



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