Advantages and problems with pregnancy registries: observations and surprises throughout the life of the International Lamotrigine Pregnancy Registry

@article{Sinclair2014AdvantagesAP,
  title={Advantages and problems with pregnancy registries: observations and surprises throughout the life of the International Lamotrigine Pregnancy Registry},
  author={S. Sinclair and M. Cunnington and J. Messenheimer and J. Weil and J. Cragan and R. Lowensohn and M. Yerby and P. Tennis},
  journal={Pharmacoepidemiology and Drug Safety},
  year={2014},
  volume={23},
  pages={779 - 786}
}
The International Lamotrigine Pregnancy Registry monitored for a signal of a substantial increase in the frequency of major congenital malformations associated with lamotrigine exposures in pregnancy over an 18‐year period. Key methodological lessons are discussed. 
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