Advantages and limitations of commonly used methods to assay the molecular permeability of gap junctional intercellular communication.

@article{Abbaci2008AdvantagesAL,
  title={Advantages and limitations of commonly used methods to assay the molecular permeability of gap junctional intercellular communication.},
  author={Muriel Abbaci and Muriel Barberi-Heyob and Walter Blondel and Francois F Guillemin and Jacques Didelon},
  journal={BioTechniques},
  year={2008},
  volume={45 1},
  pages={33-52, 56-62}
}
The role of gap junctional intercellular communication (GJIC) in regulation of normal growth and differentiation is becoming increasingly recognized as a major cellular function. GJIC consists of intercellular exchange of low molecular weight molecules, and is the only means for direct contact between cytoplasms of adjacent animal cells. Disturbances of GJIC have been associated with many pathological conditions, such as carcinogenesis or hereditary illness. Reliable and accurate methods for… CONTINUE READING