• DOI:10.1002/j.1875-9114.2012.01027.x
Corpus ID: 6406983

Advantages and Disadvantages of Etomidate Use for Intubation of Patients with Sepsis

@article{Cherfan2012AdvantagesAD,
  title={Advantages and Disadvantages of Etomidate Use for Intubation of Patients with Sepsis},
  author={Antoine J. Cherfan and Y. Arabi and H. Al-Dorzi and Lisa P. Kenny},
  journal={Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy},
  year={2012},
  volume={32}
}

• Antoine J. Cherfan, Y. Arabi, +1 author Lisa P. Kenny
• Published 2012
• Medicine
• Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy

Etomidate is a potent imidazole hypnotic used widely in single doses in the rapid sequence intubation of critically ill patients with sepsis due to its presumed hemodynamic safety, fast onset, and short duration of action. However, the literature is conflicting regarding the hemodynamic advantages of etomidate over other induction agents, and its safety in this population is a matter of strong debate in the critical care community as the drug is associated with suppression of adrenal… Expand

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