Advances of endomicroscopy for gastrointestinal physiology and diseases.

@article{Goetz2010AdvancesOE,
  title={Advances of endomicroscopy for gastrointestinal physiology and diseases.},
  author={Martin Goetz and Ralf Kiesslich},
  journal={American journal of physiology. Gastrointestinal and liver physiology},
  year={2010},
  volume={298 6},
  pages={
          G797-806
        }
}
  • M. Goetz, R. Kiesslich
  • Published 1 June 2010
  • Medicine, Biology
  • American journal of physiology. Gastrointestinal and liver physiology
Confocal endomicroscopy is a novel technique that permits in vivo microscopy of the human gastrointestinal mucosa during ongoing endoscopy, thereby providing optical virtual biopsies. Endomicroscopy has been demonstrated to reveal histological information in a multitude of diseases in the upper and lower gastrointestinal tract in vivo. Most studies have focused on inflammation and neoplasia, such as Barrett's esophagus, gastric cancer, celiac disease, Crohn's disease and ulcerative colitis, or… 
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74 Citations
Highly Influential Citations
4
Background Citations
32
Methods Citations
6
Results Citations
1

74 Citations

Citation Type

Citation Type

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  • A. Arya, B. Yan
  • Medicine
    World journal of gastrointestinal endoscopy
  • 2012
TLDR
High magnification endoscopy has shown promising results in clinical trials for Barrett's esophagus, esophageal adenocarcinoma, esphageal squamous cell cancer, gastric cancer, celiac disease, colorectal cancer, and inflammatory bowel disease.
Technicalities of Colonoscopy: Endoscopic Microscopy – Where Are We Heading?
TLDR
Reports on in vivo molecular imaging and assessment of physiological changes provide a promising glance at the future possibilities of CLE imaging.
Confocal laser endomicroscopy in inflammatory bowel diseases: future, reality or dream?
Optical endomicroscopy and the road to real-time, in vivo pathology: present and future
TLDR
Optical diagnostic technologies are emerging as clinically useful tools with the potential to set a new standard for real-time diagnosis, and are expected to eventually offer a see-and-treat paradigm, leading to improved patient care and potential cost reduction.
Confocal laser endomicroscopy: a primer for pathologists.
TLDR
How confocal laser endomicroscopy works is described, its advantages and limitations compared to cytohistologic biopsy are shown, and how it may affect the practice of pathology is explored.
Low-Cost Endomicroscopy in the Esophagus and Colon
TLDR
A case involving surveillance and guided therapy of Barrett’s esophagus is presented, followed by three cases illustrating the characteristic features of normal, inflammatory, and adenomatous tissue in the colon.
Confocal Laser Endomicroscopy: Applications in Clinical and Translational Science—A Comprehensive Review
TLDR
A comprehensive review over current applications of CLE in clinical applications and translational science allows detection and characterization of lesions and may be used for prediction of response to targeted therapy.
Confocal Laser Endomicroscopy : Applications in Clinical and Translational Science — AComprehensive Review
TLDR
A comprehensive review over current applications of CLE in clinical applications and translational science allows detection and characterization of lesions and may be used for prediction of response to targeted therapy.
Review of Confocal Fluorescence Endomicroscopy for Cancer Detection
TLDR
The aim is to achieve a real-time 3-D fluorescence imaging system that can be used for diagnostic imaging and guided biopsy procedures of oral cavity lesions in a clinical setting.
A Primer for Pathologists
TLDR
Confocal laser endomicroscopy is proving its ability to provide histology-like images of tissues in vivo to help avoid risks and costs of conventional biopsies and offers an opportunity for pathologists to find new ways to provide value and improve patient care.
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References

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TLDR
Confocal endomicroscopy is useful in the diagnosis of gastric cancer but good quality images cannot always be obtained and in the future it may allow virtual biopsy and help reduce unnecessary biopsies.
In vivo diagnosis of collagenous colitis by confocal endomicroscopy
TLDR
A confocal laser microscope (EC-3870CIFK) was designed to enable subsurface imaging of living tissue during ongoing endoscopy and allows confocal microscopy in addition to standard video endoscope.
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TLDR
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TLDR
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TLDR
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TLDR
Confocal laser endoscopy is a novel diagnostic tool to analyze living cells during colonoscopy, thereby enabling virtual histology of neoplastic changes with high accuracy and may be of crucial importance in clinical practice.
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TLDR
A rigid miniaturized probe for confocal endomicroscopy of the human liver during laparoscopy allowed in vivo microscopic analysis of healthy and diseased human liver for the first time during ongoing minilaparoscope.
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