Advances of Immune Checkpoint Inhibitors in Tumor Immunotherapy

@inproceedings{Guo2018AdvancesOI,
  title={Advances of Immune Checkpoint Inhibitors in Tumor Immunotherapy},
  author={Qiao Guo},
  year={2018}
}
Immune checkpoints are cell surface molecules that can fine-tune the immune responses, they are crucial for modulating the duration and amplitude of immune reactions while maintaining self-tolerance in order to minimize autoimmune responses. Numerous studies have demonstrated that tumors cells can directly express immune-checkpoint molecules, or induce many inhibitory molecules expression in the tumor microenvironment to inhibit the anti-tumor immunity. Releasing these brakes has emerged as an… CONTINUE READING

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