Advances in understanding benzene health effects and susceptibility.

  title={Advances in understanding benzene health effects and susceptibility.},
  author={Martyn T. Smith},
  journal={Annual review of public health},
          133-48 2 p following 148
  • Martyn T. Smith
  • Published 17 March 2010
  • Biology
  • Annual review of public health
Benzene is a ubiquitous chemical in our environment that causes acute leukemia and probably other hematological cancers. Evidence for an association with childhood leukemia is growing. Exposure to benzene can lead to multiple alterations that contribute to the leukemogenic process, indicating a multimodal mechanism of action. Research is needed to elucidate the different roles of multiple metabolites in benzene toxicity and the pathways that lead to their formation. Studies to date have… 

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