Advances in the pathophysiology of tension-type headache: From stress to central sensitization

@article{Chen2009AdvancesIT,
  title={Advances in the pathophysiology of tension-type headache: From stress to central sensitization},
  author={Yaniv Chen},
  journal={Current Pain and Headache Reports},
  year={2009},
  volume={13},
  pages={484-494}
}
  • Yaniv Chen
  • Published 2009
  • Medicine
  • Current Pain and Headache Reports
Tension-type headache (TTH) is the most common and most socioeconomically costly headache. Yet our knowledge regarding TTH pathophysiological mechanisms is still in its early stages. Psychological stress and weak coping mechanisms may initiate and propagate physiological pain via activation of second messengers in downstream substrates involved in pain. It seems that peripheral mechanisms are predominant in the episodic type (ETTH), whereas central mechanisms are involved in the chronic type… Expand
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