Advances in the genetics of sarcoidosis.

  title={Advances in the genetics of sarcoidosis.},
  author={Garrett C Smith and Isaac Brownell and Miguel A. Sanchez and Stephen D Prystowsky},
  journal={Clinical genetics},
  volume={73 5},
Sarcoidosis is an uncommon disease of granulomatous inflammation. Genetic predisposition to sarcoidosis is indicated by observations of familial clustering, increased concordance in monozygotic twins over other siblings, and variations in susceptibility and disease presentation among different ethnic groups. Published studies on sarcoidosis have investigated a variety of genetic associations. These studies used techniques ranging from classic human lymphocyte antigen genotype correlations to… CONTINUE READING