Advances in the formulations of non-injection administration of docetaxel.

@article{Zhang2014AdvancesIT,
  title={Advances in the formulations of non-injection administration of docetaxel.},
  author={Haiqun Zhang and Jinfeng Dou and Yingjie Zhai and Anchang Liu and Guangxi Zhai},
  journal={Journal of drug targeting},
  year={2014},
  volume={22 2},
  pages={87-94}
}
Docetaxel is one of the most important anti-tumor drugs and has shown powerful therapeutic activity against breast cancer, non-small cell lung cancer, prostate cancer and so on. Owing to its poor water solubility and the efflux by P-glycoprotein (P-gp) and metabolism by CYP3A4 enzymes, it is generally administered as an injection form, the only manner for the current clinical application. However, the injection bearing polysorbate 80 and ethanol may cause adverse events such as severe… CONTINUE READING