Advances in the evaluation of the neonatal brain.


Recent advances in perinatal medicine have improved the survival of preterm infants. Hypothermia provides effective neuroprotection for term asphyxiated infants. However, improving the neurodevelopmental outcome of high-risk neonates remains a challenge. For this purpose, an evaluation of the neonatal brain is essential. This issue of Brain & Development contains several studies on the evaluation of the neonatal brain that provide insight into the neonatal brain. Neuroimaging is progressing rapidly and allows the analysis of many aspects of the developing brain. Fetal magnetic resonance imaging (MRI) is an expanding field of neuroimaging. We can recognize brain abnormalities such as hydrocephalus and agenesis of the corpus callosum using fetal MRI. Ozcan et al. reported the application of diffusionweighted images (DWI) to fetal MRI [1]. They showed that the precentral gyrus was not identified until 24 weeks of gestation, was observed unilaterally in 40% and bilaterally in 60% at between 25 and 27 weeks, and was recognized in all fetuses 28 weeks or older on DWI. The identification of the precentral gyrus is useful for detecting abnormalities in the formation of gyrus structures and evaluating the presence or absence of ischemic brain damage. The results of this study will contribute to more accurate evaluation of the fetal brain. Advanced MRI analyses including diffusion tensor imaging [2], quantitative MR spectroscopy [3], and volumetry are promising measures for a detailed evaluation of the brain in high-risk neonates. Munakata et al. reported the results of volumetric MRI analysis of late-preterm and term infants [4]. They showed that late-preterm infants had a smaller gray

DOI: 10.1016/j.braindev.2012.07.004

Cite this paper

@article{Okumura2013AdvancesIT, title={Advances in the evaluation of the neonatal brain.}, author={Akihisa Okumura}, journal={Brain & development}, year={2013}, volume={35 1}, pages={2-3} }