Advances in the epidemiology, pathogenesis and management of diabetic peripheral neuropathy

@article{Tesfaye2012AdvancesIT,
  title={Advances in the epidemiology, pathogenesis and management of diabetic peripheral neuropathy},
  author={Solomon H. Tesfaye and Dinesh Selvarajah},
  journal={Diabetes/metabolism research and reviews},
  year={2012},
  volume={28 Suppl 1},
  pages={8-14}
}
Diabetic peripheral neuropathy (DPN) affects up to 50% of patients with diabetes and is a major cause of morbidity and increased mortality. Its clinical manifestations include painful neuropathic symptoms and insensitivity, which increases the risk for burns, injuries and foot ulceration. Several recent studies have implicated poor glycaemic control, duration of diabetes, hyperlipidaemia (particularly hypertryglyceridaemia), elevated albumin excretion rates and obesity as risk factors for the… CONTINUE READING
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