Advances in the epidemiology, pathogenesis, and management of Cushing's syndrome complications.

@article{Arnaldi2012AdvancesIT,
  title={Advances in the epidemiology, pathogenesis, and management of Cushing's syndrome complications.},
  author={Giorgio Arnaldi and Tatiana Mancini and Giacomo Tirabassi and Laura Trementino and Marco Boscaro},
  journal={Journal of endocrinological investigation},
  year={2012},
  volume={35 4},
  pages={434-48}
}
Cushing's syndrome (CS) is a clinical condition resulting from chronic exposure to glucocorticoid excess. As a consequence, hypercortisolism contributes significantly to the early development of systemic disorders by direct and/or indirect effects. Complications such as obesity, hypertension, diabetes, dyslipidemia, and hypercoagulability cause premature atherosclerosis and increase cardiovascular mortality. Impairment of the skeletal system is a relevant cause of morbidity and disability in… CONTINUE READING