Advances in the Development of Anti-Toxoplasma gondii Vaccines: Challenges, Opportunities, and Perspectives.

@article{Wang2019AdvancesIT,
  title={Advances in the Development of Anti-Toxoplasma gondii Vaccines: Challenges, Opportunities, and Perspectives.},
  author={Jin-Lei Wang and Nian-Zhang Zhang and Ting-Ting Li and Jun-Jun He and H. Elsheikha and Xing-Quan Zhu},
  journal={Trends in parasitology},
  year={2019},
  volume={35 3},
  pages={
          239-253
        }
}
Important progress has been made in understanding how immunity is elicited against Toxoplasma gondii - a complex pathogen with multiple mechanisms of immune evasion. Many vaccine candidates have been tested using various strategies in animal models. However, none of these strategies has delivered as yet, and important challenges remain in the development of vaccines that can eliminate the tissue cysts and/or fully block vertical transmission. In this review, we provide an overview of the… Expand
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References

SHOWING 1-10 OF 84 REFERENCES
Moving towards improved vaccines for Toxoplasma gondii
Modulation of innate immunity by Toxoplasma gondii virulence effectors
Epidemiology of and Diagnostic Strategies for Toxoplasmosis
Vaccinology in the genome era.
Innate immunity to Toxoplasma gondii infection
...
1
2
3
4
5
...