Advances in technical aspects of myocardial perfusion SPECT imaging

@article{Slomka2009AdvancesIT,
  title={Advances in technical aspects of myocardial perfusion SPECT imaging},
  author={Piotr J. Slomka and James A. Patton and Daniel S. Berman and Guido Germano},
  journal={Journal of Nuclear Cardiology},
  year={2009},
  volume={16},
  pages={255-276}
}
Although myocardial perfusion SPECT (MPS) imaging is widely used in current clinical practice, it suffers from some fundamental limitations including long image acquisition, low image resolution, and patient radiation dose. In the last two decades, MPS was performed most commonly by standard dual-head scintillation cameras with parallel-hole collimators, typically configured in a 90 detector geometry and image reconstruction based on standard filtered-back projection algorithms. The required… 
SPECT Myocardial Perfusion Imaging: Poststress, End Systolic Images and the Ongoing Effort to Improve Diagnostic Accuracy
  • H. Gewirtz
  • Physics
    The Journal of Nuclear Medicine
  • 2015
TLDR
It is appreciated for some time that apparent tracer distribution in single-photon myocardial perfusion images is much more pronounced in SPECT than in PET, and given the fundamental physics involved, PET imaging is better able to correct such errors.
Myocardial perfusion imaging: achieving high image quality in half the time or in half the radiation dose
TLDR
The technological advances that have been developed recently to cope with limitations of MPI, including the reduced imaging time and the reduction in radiation dose, both with preserved image quality are discussed.
Lower dose and shorter acquisition: Pushing the boundaries of myocardial perfusion SPECT
  • O. Gaemperli, P. Kaufmann
  • Medicine
    Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology
  • 2011
TLDR
Nuclear cardiologists have been urged to reduce patients’ radiation exposure from MPISPECT, if ever possible without increasing acquisition times and thereby reducing patient comfort.
Advances in Nuclear Cardiac Instrumentation with a View Towards Reduced Radiation Exposure
TLDR
These technologies including new single photon emission computed tomography and positron emission tomography scanners, as well as novel reconstruction software with regard to their potential for the reduction of the patient radiation dose are discussed.
Recent developments and future prospects of SPECT myocardial perfusion imaging
TLDR
It seems that SPECT would enjoy its pivotal role in spite of major threat to be replaced by fluorine-18-labeled positron emission tomography perfusion and glucose metabolism imaging agents.
Solid-State Detector SPECT Myocardial Perfusion Imaging
TLDR
State-of-the-art solid-state SPECT MPI technology and clinical applications are summarized, including emerging techniques for SPECTMPI flow estimation and the latest data providing large-scale validation of the diagnostic and prognostic value of this new technology.
Myocardial Perfusion Imaging with a Solid-State Camera: Simulation of a Very Low Dose Imaging Protocol
TLDR
The feasibility of very low dose MPI is determined by exploring the minimal count level in the myocardium required for accurate MPI, and 1.0 million counts appear to be sufficient to produce myocardial images that agree well with 8.0-million-count images on quantitative perfusion and function parameters.
Early image acquisition using a solid-state cardiac camera for fast myocardial perfusion imaging
  • J. Askew, T. Miller, M. O’Connor
  • Medicine
    Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology
  • 2011
TLDR
Overall image quality was better with fewer uninterpretable studies and a lower SRS on the rest images obtained at 60 minutes compared to early image acquisition (8-12 min minutes following isotope injection).
New Imaging Protocols for New Single Photon Emission CT Technologies
TLDR
Nuclear cardiology practitioners have several new technologies available with which to perform myocardial perfusion single photon emission CT (MPS) that offer potential for new protocols such as simultaneous dual isotope, new combinations of isotopes, stress only MPS, or dynamic first-pass imaging.
State of the Art: Solid-State Detector SPECT myocardial perfusion imaging
There has been an evolutionary leap in single photon emission computed tomography (SPECT) imaging with the advent of camera systems which utilize solid-state crystals and novel collimator designs
...
...

References

SHOWING 1-10 OF 61 REFERENCES
Development of Rapid SPECT Acquisition Protocol for Myocardial Perfusion Imaging
TLDR
This work characterize the effects of various acquisition and reconstruction protocols with the explicit aim to reduce scan time without adverse affects as compared to FBP driven protocols and finds that the detection ability is not impacted when using 6deg angular steps, and thus reducing the acquisition time by 50%, asCompared to the current method.
A novel approach to multipinhole SPECT for myocardial perfusion imaging.
TLDR
The results indicate that myocardial multipinhole tomography with 2 or more views offers an image quality and spatial resolution comparable with current rotational SPECT techniques, but with the advantage of a 5-fold increase in efficiency.
Prospective multicenter evaluation of rapid, gated SPECT myocardial perfusion upright imaging
TLDR
Rapid, gated rest–stress myocardial perfusion upright SPECT imaging may be achieved without compromising perfusion and function information.
Estimation accuracy of ejection fraction in gated cardiac SPECT/CT imaging using iterative reconstruction with 3D resolution recovery in rapid acquisition Protocols
TLDR
The estimation accuracy of the cardiac ejection fraction of gated myocardial SPECT/CT perfusion images, acquired with currently used clinical protocols, as well as rapid acquisition protocols, are evaluated.
Clinical results of a novel wide beam reconstruction method for shortening scan time of Tc-99m cardiac SPECT perfusion studies
Recent Advances in SPECT Imaging
  • M. Madsen
  • Physics
    Journal of Nuclear Medicine
  • 2007
TLDR
New clinical devices include high-count sensitivity cardiac SPECT systems that do not use conventional collimation and the introduction of diagnostic-quality hybrid SPECT/CT systems.
A triple-head solid state camera for cardiac single photon emission tomography (SPECT)
The CardiusTM-3 (C-3) camera is a triple-head small field-of-view camera dedicated to cardiac SPECT imaging. It is built on Digirad's solid-state detector technology with 6mm x 6mm CsI:Tl crystals.
Multicenter investigation comparing a highly efficient half-time stress-only attenuation correction approach against standard rest-stress Tc-99m SPECT imaging
TLDR
Stress-only imaging with HT-LSAC using the Astonish acquisition/processing method provides results equivalent to conventional rest/stress scanning and has the potential to significantly improve operational efficiency without sacrificing accuracy.
...
...