Advances in targeted and immunobased therapies for colorectal cancer in the genomic era.

@article{Seow2016AdvancesIT,
  title={Advances in targeted and immunobased therapies for colorectal cancer in the genomic era.},
  author={Heng Fong Seow and Wai Kien Yip and Theodora Fifis},
  journal={OncoTargets and therapy},
  year={2016},
  volume={9},
  pages={1899-920}
}
Targeted therapies require information on specific defective signaling pathways or mutations. Advances in genomic technologies and cell biology have led to identification of new therapeutic targets associated with signal-transduction pathways. Survival times of patients with colorectal cancer (CRC) can be extended with combinations of conventional cytotoxic agents and targeted therapies. Targeting EGFR- and VEGFR-signaling systems has been the major focus for treatment of metastatic CRC… CONTINUE READING
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