Advances in studies on the polymorphism of UGT1A1 gene in neonates with unexplained hyperbilirubinemia

@inproceedings{Hu2018AdvancesIS,
  title={Advances in studies on the polymorphism of UGT1A1 gene in neonates with unexplained hyperbilirubinemia},
  author={Meiling Hu},
  year={2018}
}
Neonatal hyperbilirubinemia is a common clinical symptom in the neonatal period. Severe jaundice can cause neonatal bilirubin encephalopathy. Clinically because severe hyperbilirubinemia more causes, the cause of hemolysis and infection is more common, this also accounted for a certain proportion of unknown reasons. UGT1A1 is a key enzyme for bilirubin metabolism, and unexplained jaundice is associated with a decrease in UGT1A1 activity caused by mutations in UGT1A1 gene, leading to neonatal… CONTINUE READING

Topics from this paper.

References

Publications referenced by this paper.
SHOWING 1-10 OF 44 REFERENCES

Clinical significance of UGT 1 A 1 genetic analysis in Chinese neonates with severe hyperbilirubinemia [ J ]

Fu Wenping, Liu Yi
  • Pediatr Neonatol
  • 2016