Advances in molecular genetics and the prevention and treatment of substance misuse: Implications of association studies of the A1 allele of the D2 dopamine receptor gene.

@article{Young2004AdvancesIM,
  title={Advances in molecular genetics and the prevention and treatment of substance misuse: Implications of association studies of the A1 allele of the D2 dopamine receptor gene.},
  author={Ross McD Young and Bruce Robert Lawford and Arni C. Nutting and Ernest Pascal Noble},
  journal={Addictive behaviors},
  year={2004},
  volume={29 7},
  pages={1275-94}
}
Substance misuse is influenced by multiple genetic and environmental factors. Recent research has identified a number of potential genetic markers of risk and those associated with drug reward substrates show particular promise. The current study reexamines the extant published data of the association between the D2 dopamine receptor (DRD2) gene minor Taq 1A (A1) allele and substance misuse risk. A series of meta-analyses was performed on 64 studies examining DRD2 A1+ allelic status and… CONTINUE READING
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