Advances in molecular diagnostic testing for central nervous system infections

@article{Houlihan2019AdvancesIM,
  title={Advances in molecular diagnostic testing for central nervous system infections},
  author={Catherine F Houlihan and Tehmina Bharucha and Judith Breuer},
  journal={Current Opinion in Infectious Diseases},
  year={2019},
  volume={32},
  pages={244–250}
}
Purpose of review Central nervous system (CNS) infections present an ongoing diagnostic challenge for clinicians, with an aetiological agent remaining unidentified in the majority of cases even in high-income settings. This review summarizes developments in a range of diagnostic methods published in the past 18 months. Recent findings Several commercial assays exist for the detection of viral, bacterial and fungal pathogens using single multiplex PCR. Multicentre validation of the Biofire… 
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10 Citations
Background Citations
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10 Citations

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  • 2022
In this article, some recent diagnostic methods applied to CSF analysis for frequent CNS infections are presented.

Faster infection diagnostics for intensive care unit (ICU) patients

This review of recent literature identified diagnostic methods for the most prevalent infections in these patients through a search of the databases PubMed, evidence-based medicine online, York University reviewers group, Cochrane, MBE-Trip, and Sumsearch using the terms: adult, clinical laboratory techniques, critical care, early diagnosis, microbiology, molecular diagnostic techniques, spectrometry and metagenomics.

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Infections

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