Advances in microfluidics for lipid nanoparticles and extracellular vesicles and applications in drug delivery systems.

@article{Maeki2018AdvancesIM,
  title={Advances in microfluidics for lipid nanoparticles and extracellular vesicles and applications in drug delivery systems.},
  author={Masatoshi Maeki and Niko Kimura and Yusuke Sato and Hideyoshi Harashima and Manabu Tokeshi},
  journal={Advanced drug delivery reviews},
  year={2018},
  volume={128},
  pages={
          84-100
        }
}
Lipid-based nanobiomaterials as liposomes and lipid nanoparticles (LNPs) are the most widely used nanocarriers for drug delivery systems (DDSs). Extracellular vesicles (EVs) and exosomes are also expected to be applied as DDS nanocarriers. The performance of nanomedicines relies on their components such as lipids, targeting ligands, encapsulated DNA, encapsulated RNA, and drugs. Recently, the importance of the nanocarrier sizes smaller than 100nm is attracting attention as a means to improve… CONTINUE READING
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