Advances in magnetic tweezers for single molecule and cell biophysics.

  title={Advances in magnetic tweezers for single molecule and cell biophysics.},
  author={Devrim Kilinc and Gil U. Lee},
  journal={Integrative biology : quantitative biosciences from nano to macro},
  volume={6 1},
Magnetic tweezers (MTW) enable highly accurate forces to be transduced to molecules to study mechanotransduction at the molecular or cellular level. We review recent MTW studies in single molecule and cell biophysics that demonstrate the flexibility of this technique. We also discuss technical advances in the method on several fronts, i.e., from novel approaches for the measurement of torque to multiplexed biophysical assays. Finally, we describe multi-component nanorods with enhanced optical… CONTINUE READING

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