Advances in hormone replacement therapy: Weight benefits of drospirenone, a 17α-spirolactone-derived progestogen

@article{Foidart2007AdvancesIH,
  title={Advances in hormone replacement therapy: Weight benefits of drospirenone, a 17$\alpha$-spirolactone-derived progestogen},
  author={Jean-Michel Foidart and Thomas Faustmann},
  journal={Gynecological Endocrinology},
  year={2007},
  volume={23},
  pages={692 - 699}
}
Hormone replacement therapy (HRT) remains the most effective treatment for menopausal symptom relief, and may provide cardiovascular benefits in younger women initiating treatment soon after menopause. However, large surveys indicate that many symptomatic women refuse or discontinue HRT prematurely owing to fear of weight gain. A continuous combined HRT containing 17β-estradiol (E2) 1 mg plus drospirenone (DRSP) 2 mg is effective in relieving menopausal symptoms and preventing postmenopausal… 

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