Advances in high-resolution imaging--techniques for three-dimensional imaging of cellular structures.

  title={Advances in high-resolution imaging--techniques for three-dimensional imaging of cellular structures.},
  author={Diane S. Lidke and Keith A. Lidke},
  journal={Journal of cell science},
  volume={125 Pt 11},
A fundamental goal in biology is to determine how cellular organization is coupled to function. To achieve this goal, a better understanding of organelle composition and structure is needed. Although visualization of cellular organelles using fluorescence or electron microscopy (EM) has become a common tool for the cell biologist, recent advances are providing a clearer picture of the cell than ever before. In particular, advanced light-microscopy techniques are achieving resolutions below the… CONTINUE READING
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