Advances in fluorescence labeling strategies for dynamic cellular imaging.

@article{Dean2014AdvancesIF,
  title={Advances in fluorescence labeling strategies for dynamic cellular imaging.},
  author={Kevin M Dean and Amy E Palmer},
  journal={Nature chemical biology},
  year={2014},
  volume={10 7},
  pages={512-23}
}
Synergistic advances in optical physics, probe design, molecular biology, labeling techniques and computational analysis have propelled fluorescence imaging into new realms of spatiotemporal resolution and sensitivity. This review aims to discuss advances in fluorescent probes and live-cell labeling strategies, two areas that remain pivotal for future advances in imaging technology. Fluorescent protein- and bio-orthogonal-based methods for protein and RNA imaging are discussed as well as… CONTINUE READING
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