Advances in drug resistance research

  title={Advances in drug resistance research},
  author={Christudas Morais},
Drug resistance continues to be a major problem in the effective treatment of many diseases. Resistance to chemotherapy, whether intrinsic or extrinsic, is the result of at least three well defined mechanisms: prevention of the interaction of drug with the target, decreased intracellular concentration of the drug due to an increased efflux or a decreased influx, and enzymatic modification or destruction of the drug. With the advancement in technology, the molecular mechanisms of drug resistance… CONTINUE READING

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