Advances in digital and physical anthropomorphic breast phantoms for x-ray imaging.

  title={Advances in digital and physical anthropomorphic breast phantoms for x-ray imaging.},
  author={Stephen J. Glick and Lynda C. Ikejimba},
  journal={Medical physics},
  volume={45 10},
PURPOSE With the advent of three-dimensional (3D) breast imaging modalities such as digital breast tomosynthesis (DBT) and dedicated breast CT (bCT), research into new anthropomorphic breast phantoms has accelerated. These breast phantoms are important for the optimization of new breast imaging systems, assessing new regulatory submissions to prove safety and effectiveness, and for developing new approaches to acceptance and constancy testing of 3D breast imaging systems. This paper provides a… 
Realistic compressed breast phantoms for medical physics applications
This work describes a method to generate compressed breast phantoms using a biomechanical finite element (FE) model from BCT volumes, by simulating physically realistic tissue deformation, and proposes a new tissue interpolation methodology which avoids interpolating the deformation fields.
Dataset of patient-derived digital breast phantoms for in-silico studies in breast computed tomography, digital breast tomosynthesis and digital mammography.
The dataset developed within the INFN AGATA project will be used for developing a platform for virtual clinical trials in x-ray breast imaging and dosimetry and will represent a valid support for introducing new breast models for dose estimates in 2D and 3D x-rays Breast imaging and as models for manufacturing anthropomorphic physical phantoms.
Anthropomorphic Physical Breast Phantom Based on Patient Breast CT Data: Preliminary Results
A novel approach for the fabrication of realistic in shape, size as well as in x-ray absorption properties 3D physical breast models by directly mimicking the radiodensity of each voxel in a computed tomography (CT) image is proposed.
Thermoplastic 3D printing technology using a single filament for producing realistic patient-derived breast models
The presented approach, based on a single FDM material, was found suitable for manufacturing of a physical breast phantom, which mimics well the 3D spatial distribution of the different breast tissues and their x-ray absorption properties.
Development of Physical Breast Phantoms for X-ray Imaging Employing 3D Printing Techniques
Physical phantoms were constructed using two 3D printing techniques: Fused Deposition Modeling and Stereolithography. Eight materials suitable for 3D printing, including thermoplastic filaments and
Effect of glandularity on the detection of simulated cancers in planar, tomosynthesis and synthetic 2D imaging of the breast using a hybrid virtual clinical trial.
It is shown that glandularity has only a small effect on the detection of calcifications, but the threshold diameter of masses was significantly larger for higher glandularity for all of the modalities tested.
Suitability of 3D printing materials for printing anthropomorphic phantoms: A simulation study
The results showed that nylon and acrylonitrile butadiene styrene 3D printing materials well represent the x-ray absorption characteristics of both glandular, adipose and skin tissues, while further investigation on suitable materials for representing the lesion characteristics is needed.
Tissue mimicking materials for imaging and therapy phantoms: a review
This review investigates the specifications that are typically being used in development of the latest TMMs and investigates the imaging modalities that have been investigated focus around CT, mammography, SPECT, PET, MRI and ultrasound.
Application of 3D Printed Anthropomorphic Phantoms for Research and Educational Purposes in Digital Radiology
The goal of this work is to investigate the feasibility of using manufactured 3D anthropomorphic models representing parts of the chest, head and breast for both, research and educational activities.
3D printing methods for radiological anthropomorphic phantoms
Three dimensional (3D) printing technology has been widely evaluated for the fabrication of various anthropomorphic phantoms during the last couple of decades. The demand for such high quality


A novel physical anthropomorphic breast phantom for 2D and 3D x‐ray imaging
A novel, realistic breast phantom can be created using an analytically defined breast model and readily available materials using a method for rapidly creating realistic, inexpensive physical anthropomorphic phantoms for use in full‐field digital mammography and digital breast tomosynthesis.
Development of realistic physical breast phantoms matched to virtual breast phantoms based on human subject data.
The development of a new suite of physical breast phantoms based on human data that offer realistic breast anatomy, patient variability, and ease of use and are a potential candidate for performing both system quality control testing and virtual clinical trials.
Development of a physical 3D anthropomorphic breast phantom.
The authors have developed a technique to produce 3D anthropomorphic breast phantoms with known ground truth, yielding highly realistic x-ray images that may serve both qualitative and quantitative performance assessments for 2D and 3D breast x-rays imaging systems.
Generation of voxelized breast phantoms from surgical mastectomy specimens.
The digital breast phantoms developed herein provide a high-resolution anthropomorphic model of the 3D uncompressed and compressed breast that are suitable for use in evaluating and optimizing tomographic breast imaging modalities.
Development of a 3D high-resolution physical anthropomorphic breast phantom
A method to fabricate a 3D physical anthropomorphic breast phantom has been developed with known ground truth in the form of a companion voxel phantom for image quality assessment of 2D and 3D breast x-ray imaging systems.
Evaluation of a breast software model for 2D and 3D X-ray imaging studies of the breast.
  • Y. Baneva, K. Bliznakova, Z. Bliznakov
  • Physics, Medicine
    Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics
  • 2017
An anthropomorphic breast model for breast imaging simulation and optimization.
A physical breast phantom for 2D and 3D x-ray imaging made through inkjet printing
The purpose of this work was to develop a new method to generate realistic physical breast phantoms using easy to obtain and inexpensive materials and it is promising for use in imaging studies and developing QC protocols.
X-ray properties of an anthropomorphic breast phantom for MRI and x-ray imaging
The phantom is a useful tool for quantitative evaluation of two- and three-dimensional x-ray and MRI breast imaging modalities for the purpose of lesion detection and characterization and is shown to be comparable to those of breast tissue.
A statistically defined anthropomorphic software breast phantom.
The authors describe a method for enhancing an existing digital anthropomorphic breast phantom by adding binarized power-law noise to a limited area of the breast, which qualitatively improves its realism.