Advances in development of a contraceptive vaccine against human chorionic gonadotropin

  title={Advances in development of a contraceptive vaccine against human chorionic gonadotropin},
  author={Gursaran P. Talwar and Jagdish Chandra Gupta and Susana B. Rulli and Radhey Shyam Sharma and Kripa N. Nand and Atmaram H. Bandivdekar and Nishu Atrey and Priyanka Singh},
  journal={Expert Opinion on Biological Therapy},
  pages={1183 - 1190}
Introduction: There is continuing need for contraceptives. According to World Health Organization, 210 million pregnancies occur each year, out of which some 80 million are unintended. A vaccine offering privacy and periodic intake would be an attractive proposition. Areas covered: The article is a brief review of three vaccines developed against human chorionic gonadotropin (hCG) with progressively better attributes. Clinical trials have proven in more than one country the complete safety and… 
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Phase I clinical trials with three formulations of anti-human chorionic gonadotropin vaccine.
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The immunogenicity of the conjugate prepared from "processed" beta-subunit of human chorionic gonadotropin (choriogonadotropin, HCG) and tetanus toxoid has been studied in animals and a human
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Regain of Fertility and Normality of Progeny Born During Below Protective Threshold Antibody Titers in Women Immunized With the HSD‐hCG Vaccine
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