Advances in continuous renal replacement therapy: citrate anticoagulation update.

@article{Tolwani2012AdvancesIC,
  title={Advances in continuous renal replacement therapy: citrate anticoagulation update.},
  author={Ashita J Tolwani and Keith M. Wille},
  journal={Blood purification},
  year={2012},
  volume={34 2},
  pages={88-93}
}
Because of the potential side effects of heparin, methods of regional citrate anticoagulation (RCA) for continuous renal replacement therapy (CRRT) have been gaining wider acceptance with the development of simplified and safer protocols. Advantages of RCA include the avoidance of systemic anticoagulation and heparin-induced thrombocytopenia. The disadvantage is that citrate can add complexity and labor intensity to CRRT. Frequent monitoring of electrolytes, ionized calcium, and acid-base… CONTINUE READING