Advances in asthma, allergy mechanisms, and genetics in 2006.

  title={Advances in asthma, allergy mechanisms, and genetics in 2006.},
  author={Fred D. Finkelman and Donata Vercelli},
  journal={The Journal of allergy and clinical immunology},
  volume={120 3},
This review discusses the main advances in animal models of allergic airway disease and genetics of asthma and allergy published in the Journal in 2006. This work highlighted and extended what has become the central dogma of allergic pathogenesis by highlighting the mechanisms involved in inducing a T(H)2 response and in determining how T(H)2 cytokines induce the allergic airway disease phenotype. By so doing, they have identified a considerable number of potential therapeutic targets. Genetic… CONTINUE READING