Advances in antifibrotic therapy.

  title={Advances in antifibrotic therapy.},
  author={Zahra Ghiassi-Nejad and Scott L Friedman},
  journal={Expert review of gastroenterology & hepatology},
  volume={2 6},
Sustained progress in defining the molecular pathophysiology of hepatic fibrosis has led to a comprehensive framework for developing antifibrotic therapies. Indeed, the single greatest limitation in bringing new drugs to the clinical setting is a lack of clarity regarding clinical trial and treatment end points, not a lack of promising agents. A range of treatments, including those developed for other indications, as well as those specifically developed for hepatic fibrosis, are nearing or in… CONTINUE READING