Advances in Imaging Brain Metabolism.

  title={Advances in Imaging Brain Metabolism.},
  author={Fahmeed Hyder and Douglas L. Rothman},
  journal={Annual review of biomedical engineering},
Metabolism is central to neuroimaging because it can reveal pathways by which neuronal and glial cells use nutrients to fuel their growth and function. We focus on advanced magnetic resonance imaging (MRI) and magnetic resonance spectroscopy (MRS) methods used in brain metabolic studies. 17O-MRS and 31P-MRS, respectively, provide rates of oxygen use and ATP synthesis inside mitochondria, whereas 19F-MRS enables measurement of cytosolic glucose metabolism. Calibrated functional MRI (fMRI), an… CONTINUE READING
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