Advances in Gene Delivery Systems

@article{Kamimura2011AdvancesIG,
  title={Advances in Gene Delivery Systems},
  author={Kenya Kamimura and Takeshi Suda and Guisheng Zhang and Professor Dexi Liu},
  journal={Pharmaceutical Medicine},
  year={2011},
  volume={25},
  pages={293-306}
}
The transfer of genes into cells, both in vitro and in vivo, is critical for studying gene function and conducting gene therapy. Methods that utilize viral and nonviral vectors, as well as physical approaches, have been explored. Viral vector-mediated gene transfer employs replication-deficient viruses such as retrovirus, adenovirus, adeno-associated virus and herpes simplex virus. A major advantage of viral vectors is their high gene delivery efficiency. The nonviral vectors developed so far… CONTINUE READING
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