Advances in Cancer Research

  title={Advances in Cancer Research},
  author={J H Fowler},
  journal={British Journal of Cancer},
  pages={150 - 151}
The biologist will be confused on the histological threshold criteria used to diagnose malignancy in colonic adenomas. For severe dysplasia invading the mucosal connective tissue but not the muscularis mucosae 'the most accurate descriptive term is "intramucosal carcinoma"'. But 'To prevent confusion the term "intramucosal carcinoma" is best avoided in the colon.' The authors believe, perhaps correctly, that metastasis of these lesions occurs by lymphatic channels only, that there are none in… CONTINUE READING