• Published 1999

Advances in Brief Prostate-localized and Androgen-regulated Expression of the Membrane-bound Serine Protease TMPRSS 2 1

@inproceedings{Lin1999AdvancesIB,
  title={Advances in Brief Prostate-localized and Androgen-regulated Expression of the Membrane-bound Serine Protease TMPRSS 2 1},
  author={Biaoyang Lin and Camari Ferguson and James Thomas White and Shunyou Wang and Robert L. Vessella and Lawrence D. True and Leroy Hood and Peter S. Nelson},
  year={1999}
}
Genes regulated by androgenic hormones are of critical importance for the normal physiological function of the human prostate gland, and they contribute to the development and progression of prostate carcinoma. We used cDNA microarrays containing 1500 cDNAs to profile transcripts regulated by androgens in prostate cancer cells and identified the serine proteaseTMPRSS2as a gene exhibiting increased expression upon exposure to androgens. TheTMPRSS2gene is located on chromosome 21 and contains… CONTINUE READING

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