Advances in Brief Increased Expression of Estrogen Receptor b mRNA in Tamoxifen-resistant Breast Cancer Patients 1

Abstract

Tamoxifen is currently the first-line therapy for treatment of hormonedependent breast cancer. However, despite initial benefits, most patients eventually relapse. Two groups of patients were identified: (a) a tamoxifen-sensitive group (n 5 8); and (b) a tamoxifen-resistant group (n 5 9). Using reverse transcription-PCR, the relative expression of mRNA for… (More)

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