Advances and challenges in treatment and prevention of ischemic stroke.

@article{Grossman2013AdvancesAC,
  title={Advances and challenges in treatment and prevention of ischemic stroke.},
  author={Aaron W Grossman and J P Broderick},
  journal={Annals of neurology},
  year={2013},
  volume={74 3},
  pages={363-72}
}
We review recent advances in the treatment and prevention of acute ischemic stroke, including the current state of endovascular therapy, in light of 5 randomized controlled trials published this past year. Although no benefit of endovascular therapy over intravenous (IV) recombinant tissue plasminogen activator (rt-PA) has been demonstrated, endovascular therapy is an appropriate treatment for acute ischemic stroke patients within the t-PA window who are ineligible for IV t-PA but have a large… CONTINUE READING