Advances Pertaining to the Pharmacology and Interactions of Irreversible Nonselective Monoamine Oxidase Inhibitors

@article{Gillman2011AdvancesPT,
  title={Advances Pertaining to the Pharmacology and Interactions of Irreversible Nonselective Monoamine Oxidase Inhibitors},
  author={P. Gillman},
  journal={Journal of Clinical Psychopharmacology},
  year={2011},
  volume={31},
  pages={66-74}
}
  • P. Gillman
  • Published 2011
  • Chemistry, Medicine
  • Journal of Clinical Psychopharmacology
    • Recent advances clarifying the pharmacology and interactions of irreversible nonselective monoamine oxidase inhibitors that have not been considered in depth lately are discussed. These new data elucidate aspects of enzyme inhibition and pharmacokinetic interactions involving amine oxidases, cytochrome P450 enzymes, aminotransferases (transaminases), and decarboxylases (carboxy-lyases) and the effects of tyramine. Phenelzine and tranylcypromine remain widely available, and many publications… CONTINUE READING
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    44 Citations
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    An update on amine oxidase inhibitors: Multifaceted drugs
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    Attenuation of the effects of oxidative stress by the MAO-inhibiting antidepressant and carbonyl scavenger phenelzine.
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    Inhibition of Tryptophan Hydroxylases and Monoamine Oxidase-A by the Proton Pump Inhibitor, Omeprazole—In Vitro and In Vivo Investigations
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    Update on the pharmacology of selective inhibitors of MAO-A and MAO-B: focus on modulation of CNS monoamine neurotransmitter release.
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    Current Place of Monoamine Oxidase Inhibitors in the Treatment of Depression
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    Monoamine oxidase inhibitors and neuroprotection: a review.
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    Tranylcypromine in mind (Part I): Review of pharmacology
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    Selective inhibitors of monoamine oxidase type B and the "cheese effect".
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    "Much ado about nothing": monoamine oxidase inhibitors, drug interactions, and dietary tyramine.
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    Key Targets for Multi-Target Ligands Designed to Combat Neurodegeneration
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    An evaluation of potential mechanism-based inactivation of human drug metabolizing cytochromes P450 by monoamine oxidase inhibitors, including isoniazid.
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