Advanced protein crystallization using water-soluble ionic liquids as crystallization additives

@article{Hekmat2007AdvancedPC,
  title={Advanced protein crystallization using water-soluble ionic liquids as crystallization additives},
  author={Dariusch Hekmat and Dirk Hebel and Sebastian Joswig and Michael F. W. Schmidt and Dirk Weuster-Botz},
  journal={Biotechnology Letters},
  year={2007},
  volume={29},
  pages={1703-1711}
}
The application of five water-soluble, halogen-free, alkylammonium-based ionic liquids (ILs) as additives for advanced crystallization of lysozyme was investigated. Their biocompatibility was determined by long-term measurement of the overall mean relative enzyme activities. These were maximally reduced by about 10–15% when up to 200 g IL l−1 was added… CONTINUE READING