Advanced prostate cancer—a case for adjuvant differentiation therapy

@article{Rane2012AdvancedPC,
  title={Advanced prostate cancer—a case for adjuvant differentiation therapy},
  author={Jayant K. Rane and Davide Pellacani and Norman J. Maitland},
  journal={Nature Reviews Urology},
  year={2012},
  volume={9},
  pages={595-602}
}
The development of novel therapies such as abiraterone acetate and sipuleucel-T has improved the outlook for patients with advanced-stage and castration-resistant prostate cancer. However, the beneficial effects of these drugs are only measured in months. Moreover, the National Institute for Health and Clinical Excellence in the UK had ruled that the use of abiraterone acetate was not cost-effective before cost revision by the manufacturers. The FDA statement asserting that the use of 5… 

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