Advanced molecular design of biopolymers for transmucosal and intracellular delivery of chemotherapeutic agents and biological therapeutics.

@article{Liechty2011AdvancedMD,
  title={Advanced molecular design of biopolymers for transmucosal and intracellular delivery of chemotherapeutic agents and biological therapeutics.},
  author={William B Liechty and Mary E Caldorera-Moore and Margaret A. Phillips and Cody A Schoener and Nicholas A Peppas},
  journal={Journal of controlled release : official journal of the Controlled Release Society},
  year={2011},
  volume={155 2},
  pages={119-27}
}
Hydrogels have been instrumental in the development of polymeric systems for controlled release of therapeutic agents. These materials are attractive for transmucosal and intracellular drug delivery because of their facile synthesis, inherent biocompatibility, tunable physicochemical properties, and capacity to respond to various physiological stimuli. In this contribution, we outline a multifaceted hydrogel-based approach for expanding the range of therapeutics in oral formulations from… CONTINUE READING
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