Advanced glycoxidation and lipoxidation end products (AGEs and ALEs): an overview of their mechanisms of formation

  title={Advanced glycoxidation and lipoxidation end products (AGEs and ALEs): an overview of their mechanisms of formation},
  author={Giulio Vistoli and Danilo De Maddis and Ana {\vC}ipak and Neven Žarkovi{\'c} and Marina Carini and Giancarlo Aldini},
  journal={Free Radical Research},
  pages={27 - 3}
Abstract Advanced lipoxidation end products (ALEs) and advanced glycation end products (AGEs) have a pathogenetic role in the development and progression of different oxidative-based diseases including diabetes, atherosclerosis, and neurological disorders. AGEs and ALEs represent a quite complex class of compounds that are formed by different mechanisms, by heterogeneous precursors and that can be formed either exogenously or endogenously. There is a wide interest in AGEs and ALEs involving… 

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