Advanced glycation endproduct crosslinking in the cardiovascular system: potential therapeutic target for cardiovascular disease.

Abstract

Advanced glycation endproducts (AGEs) are formed by a reaction between reducing sugars and biological amines. Because of their marked stability, glycated proteins accumulate slowly over a person's lifespan, and can contribute to age-associated structural and physiological changes in the cardiovascular system such as increased vascular and myocardial… (More)

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Cite this paper

@article{Zieman2004AdvancedGE, title={Advanced glycation endproduct crosslinking in the cardiovascular system: potential therapeutic target for cardiovascular disease.}, author={Susan J. Zieman and David A. Kass}, journal={Drugs}, year={2004}, volume={64 5}, pages={459-70} }